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Simon Pagenaud's career was cut short eight races into the 2023 season when he was badly injured in a crash that caused ...
Cancer is cruel. It doesn’t care that you’re only 37, that you're the mother of a little girl who is your entire world. So Elissa vowed to fight.
Personalized medicine is already a reality in clinical practice, and CAR-T cell therapy is one of its most promising tools.
Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg have identified a previously undocumented, organ-specific toxicity linked to CD19-targeted CAR T-cell therapy in autoimmune disease.
Local immune effector cell–associated toxicity syndrome is a newly identified side effect observed in many patients receiving CD19-targeting CAR T-cell therapy for autoimmune conditions.
Relative survival increased from 64% to 66%, overall survival from 54% to 55%, and lymphoma-specific survival from 64% to 66%.
As people age, their immune systems become less efficient, posing a challenge for cancer therapies that rely on harnessing immune cells.
A Ludwig Cancer Research study has discovered that the metabolic decline that accompanies aging impairs the efficacy of CAR-T cell therapy, an immunotherapy in which T cells of the immune system are ...
At COMy 2025, researchers highlighted barriers to EMA-approved CAR T-cell therapy access due to age, comorbidities, and ...
In 2018, England was the first country in Europe to provide access to a CAR-T cell therapy to treat these blood cancers, enabled via the Cancer Drugs Fund (CDF). Since then, over 500 patients in ...
Like other CAR-Ts, Calibr's therapy is manufactured from a patient's own T-cells, which are harvested and genetically modified to fight cancer before being reintroduced into the body. However ...