
Deep brain stimulation: current challenges and future directions
Deep brain stimulation (DBS) is opening new therapeutic possibilities for neurological and psychiatric disorders. DBS is enabling neuroscientists to obtain direct measures of cellular activity and to probe the function of neural circuits.
Cleveland Clinic Study Shows Deep Brain Stimulation …
Aug 14, 2023 · A first-in-human trial of deep brain stimulation (DBS) for post-stroke rehabilitation patients by Cleveland Clinic researchers has shown that using DBS to target the dentate nucleus – which regulates fine-control of voluntary movements, cognition, language, and sensory functions in the brain – is safe and feasible.
Deep brain stimulation: An overview of history, methods, and …
Deep brain stimulation (DBS) has revolutionised treatment of movement disorders over recent decades, providing remarkable relief to patients with Parkinson’s disease (PD) and other profoundly debilitating disorders.
Deep brain stimulation: current challenges and future directions
Jan 25, 2019 · Deep brain stimulation (DBS) is opening new therapeutic possibilities for neurological and psychiatric disorders. DBS is enabling neuroscientists to obtain direct measures of cellular activity...
A man volunteered to get brain implants for depression. Hear his …
6 days ago · Scientists are studying an experimental treatment for severe depression called deep brain stimulation. As a volunteer for a study, Jon Nelson often takes the train from Pennsylvania to a research ...
Thalamic deep brain stimulation in traumatic brain injury: a …
The primary objective of this feasibility study was to test the safety and efficacy of deep brain stimulation within the CL and the associated medial dorsal tegmental (CL/DTTm) tract.Six participants with msTBI, who were between 3 and 18 years post-injury, underwent surgery with electrode placement guided by imaging and subject-specific ...
Chronic adaptive deep brain stimulation versus conventional stimulation …
Aug 19, 2024 · Here we present the results of a blinded randomized cross-over pilot trial aimed at determining the neural correlates of specific motor signs in individuals with PD and the feasibility of using...
Thalamic deep brain stimulation in traumatic brain injury: a …
Dec 4, 2023 · A phase 1 feasibility trial shows that bilateral deep brain stimulation within the central lateral thalamus can be safely applied and is associated with improved executive control.
Insights on limits of non-invasive deep-brain stimulation
Feb 5, 2025 · The study obtains evidence suggesting that parvalbumin (PV) neurons are activated with TI stimulation in both the deep and shallow brain. However, in the shallow brain, inhibitory effects of PV neurons are strong, preventing excitatory pyramidal (Pyr) neurons from activating. TI stimulation causes high activation of PV neurons in shallow brain ...
Study to test deep brain stimulation for bipolar depression
Jan 16, 2025 · In the new study, the researchers will evaluate whether placing electrodes in the same brain circuit implicated in OCD — a brain structure called the ventral capsule/ventral striatum (VC/VS) — can reduce or prevent depression without triggering mania.