Researchers have found a ‘clear genetic trigger for obesity’ that ...
WEBJun 21, 2024 · Researchers were able to locate a specific gene variant correlated with some people's weight gain, a new study showed. Obesity isn’t just a matter of food and exercise — it may be in your ...
New genetic cause of obesity could help guide treatment
WEBJun 20, 2024 · Scientists have discovered a new cause of why people who lack a specific blood group are genetically predisposed to be overweight or obese.
Scientists Identify Rare Gene Variants That Can Increase Your Risk …
WEBApr 9, 2024 · A study led by MRC researchers found genetic variants in the BSN and APBA1 genes significantly impact obesity risk, with these effects notably manifesting in adulthood. Utilizing data from over 500,000 individuals, this research suggests a novel biological mechanism for obesity linked to brain signaling and proposes potential new …
Protein-truncating variants in BSN are associated with severe adult ...
WEBApr 4, 2024 · Analyses of whole-exome sequencing data identify rare loss-of-function variants in BSN associated with adult-onset obesity, type 2 diabetes and fatty liver disease, with stronger effect sizes...
New genes associated with adult-onset obesity - Nature
WEBApr 24, 2024 · Genetic association testing identified nine genes that had a significant association with BMI in adulthood, of which four had not previously been reported. Protein-truncating variants in these ...
Specific genetic variant may help prevent obesity - ScienceDaily
WEBDec 7, 2023 · A preclinical study shows that a specific human genetic variant of a receptor that stimulates insulin release may help individuals be more resistant to obesity. The researchers discovered that...
Rare gene variants conferring up to 6-fold increase in obesity risk ...
WEBApr 4, 2024 · The genetic variants we identify in BSN confer some of the largest effects on obesity, type 2 diabetes and fatty liver disease observed to date and highlight a new biological mechanism regulating appetite control.”
Specific genetic variant may help prevent obesity
WEBDec 12, 2023 · The study, published Nov. 2 in Molecular Metabolism, provides new insight into how human genetic variations affect an individual’s susceptibility to weight gain. The researchers developed mice with a human genetic variant in the glucose-dependent insulinotropic polypeptide (GIP) receptor associated with leaner body mass index (BMI).
Expanding the genetic landscape of obesity - Cell Press
WEBSep 13, 2023 · The identification of sex- and age-specific genetic effects on obesity highlights the importance of considering these factors in future genetic studies, which can help uncover additional genetic factors contributing to disease susceptibility and improve our understanding of the interplay between genetic and environmental factors in disease ...
Specific Genetic Variant May Help Prevent Obesity
WEBDec 7, 2023 · The study, posted online in Molecular Metabolism on Nov. 2, provides new insight into how human genetic variations affect an individual’s susceptibility to weight gain. The researchers developed mice with a human genetic variant in the glucose-dependent insulinotropic polypeptide (GIP) receptor associated with leaner body mass index (BMI).