Researchers have found a ‘clear genetic trigger for obesity’ that ...
Jun 21, 2024 · Experts have long known there is a genetic component to obesity, and a new study identified one particular gene that may be behind it.
New genetic cause of obesity could help guide treatment
Jun 20, 2024 · People who lack a specific blood group (Vel-negative) have a genetic variant that disables the SMIM1 gene and reduces their energy expenditure. This could lead to new treatments for obesity, such...
Scientists Identify Rare Gene Variants That Can Increase Your Risk …
Apr 9, 2024 · A study by MRC researchers found that genetic variants in these two genes can increase obesity risk by up to six times, especially in adulthood. The variants affect brain signaling and may be involved in neurodegeneration and appetite control.
New genetic cause of obesity could help guide treatment
Jun 20, 2024 · People who lack both copies of the SMIM1 gene, which encodes a blood group protein, have higher body weight and lower energy expenditure. The researchers suggest that a thyroid drug may help treat obesity in this group and hope to test it in a clinical trial.
Researchers have found a ‘clear genetic trigger for obesity
Researchers discovered a specific gene variant that affects thyroid function and energy expenditure, causing some people to gain weight. The study suggests that this genetic trigger may be...
Massive DNA study finds rare gene variants that protect against obesity
Jul 1, 2021 · Other work has found thousands of genetic variants, each of which has a tiny impact on body weight; together, they can significantly increase the likelihood of obesity. In the new study, researchers sequenced the genomes of more than 640,000 people from Mexico, the United States, and the United Kingdom, homing in on only the exome—the part of ...
Scientists identify rare gene variants that confer up to 6-fold ...
In addition, unlike the obesity genes previously identified, variants in BSN and APBA1 are not associated with childhood obesity. This has led the researchers to believe that they may have …
Large-scale genetic study identifies genes that increase risk of ...
Feb 22, 2021 · A large-scale genetic study identified 62 regions of the genome that are associated with increased risk of obesity but also protect against cardiometabolic diseases. The study reveals novel ways in which excess body fat can …
Rare gene variants conferring up to 6-fold increase in obesity risk ...
Apr 4, 2024 · A study by MRC researchers found that genetic variants in these genes can raise the risk of obesity up to six times and affect appetite control. The variants are not involved in the leptin-melanocortin pathway and may indicate a new biological mechanism for obesity.
Study identifies genetic variants with profound impact on obesity …
The genetic variants we identify in BSN confer some of the largest effects on obesity, type 2 diabetes and fatty liver disease observed to date and highlight a new biological mechanism …